Apolipoprotein E Genotype in Korean Schizophrenic Patients

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Apolipoprotein E genotype in Korean schizophrenic patients.

The apolipoprotein E (APOE) epsilon4 allele is a known risk factor for the development of Alzheimer's disease, however, an association of the APOE genotype with schizophrenia is controversial. We investigated the association in 60 Korean schizophrenic patients and 60 healthy controls. APOE genotypes were identified by reverse hybridization-based line probe assay. There were significant differen...

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Apolipoprotein E genotype in patients with Alzheimer's disease.

OBJECTIVE To explore the frequency and significance of ApoE gene polymorphisms in patients with sporadic Alzheimer's disease (AD). METHODS Single nucleotide polymorphisms of the ApoE gene were analyzed in 32 cases of AD and 26 controls, using PCR and gene sequencing. RESULTS The single nucleotide polymorphism of ApoE gene 462C/G was significantly associated with AD (P < 0.05). CONCLUSIONS...

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Dementia, quantitative neuroimaging, and apolipoprotein E genotype.

BACKGROUND AND PURPOSE Quantitative MR imaging differences in an elderly population of subjects with various clinical disorders (including dementia, particularly Alzheimer's disease and vascular dementia) and disorders of mild cognitive impairment were examined. Potential quantitative MR differences were assessed by presence or absence of the apolipoprotein E (APOE) epsilon4 allele and by level...

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Apolipoprotein E genotype and coronary heart disease.

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ژورنال

عنوان ژورنال: Journal of Korean Medical Science

سال: 2001

ISSN: 1011-8934,1598-6357

DOI: 10.3346/jkms.2001.16.6.781